Is it always sleepy in the daytime? Maybe because of your obesity and depression
Phoenix Technology News Beijing time May 12th news, according to the Science Daily newspaper, according to the Penn State University medical school In addition to lack of sleep, obesity and depression are also the underlying causes of regular sleepiness, according to a recent study by researchers. They say these findings can promote the development of more personalized sleeping drugs for patients with excessive daytime sleepiness (EDS).
about 30% of the general public has experienced EDS, that is, drowsiness or drowsiness during the day, including irresistible drowsiness. Excessive fatigue during daytime may reduce work efficiency, increase error rate and absenteeism, which may lead to more serious problems, such as car accidents.
previous studies suggest that EDS is associated with obesity, depression and sleep apnea, but this latest study is the first to use physiological sleep data to speculate on the causes and investigate the mechanisms. This is also the first EDS observational study in the past few years.
the researchers measured the baseline EDS self-report of 1395 men and women and then tested it again after an average of 7.5 years. The subjects completed a complete sleep history and physiological examination, and received a one night assessment in a sleep laboratory. Researchers also recorded sleep, physical and mental health problems and substance use to determine whether these subjects were physically and mentally healthy.
"obesity and weight gain can predict who will have daytime sleepiness," said Julio fnandez - Mendoza, Professor of psychiatry at the sleep research and treatment center at the Penn State University School of medicine in the United States. "In addition, weight loss also predicts who will no longer experience daytime sleepiness, which further proves the causal relationship between them." The correlation between
physical body mass index (BMI) and sleepiness is not related to the length of sleep, which means that obese people may feel sleepy during the day, regardless of how long they sleep at night.
obesity is also associated with sleep apnea, which refers to the condition of stopping breathing during sleep. One sign of sleep apnea is daytime sleepiness. Although we naturally conclude that sleep apnea can lead to fatigue in obese people, this study negates this hypothesis. The researchers published these findings in the journal Sleep.
"compared with sleep apnea, weight is better predictor of EDS," Fernandez Mendoza said. "This data is consistent with previous studies that show that continuous positive airway pressure ventilation (CPAP) machines greatly reduce the number of apnea during sleep at night for people with sleep apnea, but it does not effectively reduce daytime sleepiness - which is probably due to the fact that continuous positive airway pressure does not help to reduce weight loss.
the main potential mechanism of excessive fatigue in obese people is probably low chronic inflammation. Adipocytes, especially those from abdominal fat, produce immune compounds called cell living elements, which can lead to a variety of effects, including increasing sleepiness.
the depressed subjects in this study had a higher frequency of EDS. Physiological sleep disorders, including longer periods of sleep and waking up at night, account for their daily sleepiness.
"people with depression generally think it's hard to let the brain relax, so it's likely to have a high stress hormone," said Fernand Mendoza. "We think the mechanism that plays a role is alertness, that is, simple bed but vigilant. In other words, people with depression often feel tired during the day, but they don't have to sleep."
researchers also found that a small number of people with EDS had central nervous system with physiological lethargy disorder. They sleep more than average at night, partly because they fall asleep faster than normal people. "Too much sleep during the day has great implications for public health and policies," Fernandez Mendoza said. Fatigue and sleepiness are the most common causes of lower productivity and fatal car accidents. In our research, through different mechanisms, we associate obesity and depression - a growing variety of disorders - associated with daytime sleepiness, in fact, we find that weight loss individuals are no longer complaining of daytime sleepiness.
these findings suggest that the use of generic methods for the treatment of EDS in the long run is often a drug that promotes sleep or prolongs sleep time - and will end in failure. "In medicine, it's widely believed that if you see sleepiness in the daytime, it's because you haven't slept well at night," explains Fernandez, Mendoza. "We need to start abandoning this stereotype now. If we continue to think that the only reason for sleeping too much during the day is that people are not getting enough sleep, then we will not see the forest. Drowsiness mainly includes obese people, depressed patients and, to a certain extent, people with physiological disorders. By paying close attention to our patients, we can start personalized sleep medicine. " (compiling / Yan Yan Liu Xing)