Poor diet during pregnancy or increased risk of diabetes in future generations

time:11-03-16 forum:
  Reprinted from http://paper.sciencenet.cn/htmlpaper/2011391563128315468.shtm
source: Xinhua net Huang Kun

a new animal experiment in the UK shows that poor diet can affect the genetic function of offspring and thus increase the risk of II type diabetes in offspring.

researchers at the University of Cambridge, Britain, and other institutions of University of Cambridge reported in the new issue of the National Academy of Sciences (PNAS) that the risk of II diabetes in the offspring of the experimental rats with the same amount of protein intake was higher than that of the contrast group.

analysis showed that the poor diet structure of pregnant rats affected the gene function of offspring. The function of a Hnf4a gene, which is known as the gene, is suppressed in the offspring of the mice born with insufficient protein intake during pregnancy, which plays an important role in the development of the pancreas and insulin production, and its function is affected to increase the risk of diabetes.


researcher Susan Ozan said that the mother's diet was known to be very important to offspring during pregnancy, but it was not very clear about the mechanism before, and the study revealed a mechanism for the long-term effects of pregnancy through genes on the health of offspring. Although this research is still in animal experiment stage, the result is enough to remind expectant mothers to keep healthy and reasonable diet structure.

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